Adalimumab in severe and acute sciatica
نویسندگان
چکیده
منابع مشابه
Adalimumab in severe and acute sciatica: a multicenter, randomized, double-blind, placebo-controlled trial.
OBJECTIVE Based on several experimental results and on a preliminary study, a trial was undertaken to assess the efficacy of adalimumab, a tumor necrosis factor alpha inhibitor, in patients with radicular pain due to lumbar disc herniation. METHODS A multicenter, double-blind, randomized controlled trial was conducted between May 2005 and December 2007 in Switzerland. Patients with acute (dur...
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This 32-year-old-man was admitted to the emergency department because of S1 left acute sciatica. An emergency CT-scan showed a highly probable appearance of herniated disc in L5-S1 level (A). The patient was operated without finding disc herniation, but an aspect of anterior and posterior epidural abscess compressing the dural sheath at L5-S1. Medullary MRI showed after the up and the down exte...
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Results When Enbrel plus Methotrexate was started she got into remission. After one year of this therapy, she presented uveitis in both eyes, so oral steroids were started again. She obtained only partial ocular improvement, even when she received Infliximab associated with Methotrexate. Meantime she underwent cataract surgery with visus reduction. After one year, Infliximab was suspended becau...
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Tumor necrosis factor-α inhibitors may induce various cutaneous side effects including eczematous-like lesions. The management of such side effects can be challenging. Herein, we report a case of a 55-year-old man who had a flare-up and subsequent improvement of atopic dermatitis during treatment of severe psoriasis with adalimumab.
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ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 2010
ISSN: 0003-4967
DOI: 10.1136/ard.2010.129643q